Article
Role of anti-HBs in functional cure of HBeAg+ chronic hepatitis B patients infected with HBV genotype A.
Journal of hepatology - 1 Jan 2022
Xu Hui, Locarnini Stephen, Wong Darren, Hammond Rachel, Colledge Danni, Soppe Sally, Huynh Thao, Shaw Tim, Thompson Alexander J, Revill Peter A, Hogarth P Mark, Wines Bruce D, Walsh Renae, Warner Nadia
Abstract excerpt
BACKGROUND & AIMS: HBsAg-specific antibody responses are difficult to detect during chronic hepatitis B infection (CHB) and are often overlooked. The aim of this study was to examine whether anti-HBs may be involved in functional cure (FC) by profiling anti-HBs responses in patients with CHB using a panel of specific assays. METHODS: Longitudinal serum samples were obtained from 25 patients with CHB who were...
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