Article
Escape hepatitis B virus mutations in recipients of antibody to hepatitis B core antigen-positive liver grafts receiving hepatitis B immunoglobulins.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jul 2010
Roche Bruno, Roque-Afonso Anne-Marie, Sebagh Mylene, Delvart Valerie, Duclos-Vallee Jean Charles, Castaing Denis, Samuel Didier
Abstract excerpt
A variety of prophylactic strategies are used to prevent the risk of hepatitis B virus (HBV) transmission from antibody to hepatitis B core antigen (anti-HBc)-positive donors. The mechanisms underlying the failure of HBV immunoglobulin monoprophylaxis have been poorly evaluated. Seventy-seven anti-HBc-positive grafts were used in 21 hepatitis B surface antigen (HBsAg)-positive recipients and 56 HBsAg-negative...
Topics
- Adolescent
- Adult
- Aged
- Antiviral Agents
- Hepatitis B
- Hepatitis B Surface Antigens
- Humans
- Immunoglobulins
- Incidence
- Lamivudine
