Article
A molecular analysis of viral persistence in surface antigen-negative chronic hepatitis B.
Hepatology (Baltimore, Md.) - 1 Mar 1996
Kato J, Hasegawa K, Torii N, Yamauchi K, Hayashi N
Abstract excerpt
To identify the mechanisms of viral persistence in patients with chronic hepatitis B after the acquisition of anti-hepatitis B surface antigen antibodies (antiHBs), we serially analyzed the nucleotide sequence of the envelope region in a cohort of infected patients. Four patients with histological diagnoses of chronic hepatitis B who had at least 5 years of observance by our hospital staff were studied. All but...
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