Article
Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment.
Developmental biology - 1 Nov 2010
Bialecka Monika, Wilson Valerie, Deschamps Jacqueline
Abstract excerpt
Cdx transcription factors are required for axial extension. Cdx genes are expressed in the posterior growth zone, a region that supplies new cells for axial elongation. Cdx2(+/-)Cdx4(-/-) (Cdx2/4) mutant embryos show abnormalities in axis elongation from E8.5, culminating in axial truncation at E...
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