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Article

Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice.

Development (Cambridge, England) - 1 Aug 2008

Gaunt Stephen J, Drage Deborah, Trubshaw Richard C

Abstract excerpt

To investigate the link between Cdx protein concentration and axial patterning in embryos, we made lines of mice OE1, OE2 and OE4 that overexpress each of the Cdx genes Cdx1, Cdx2 and Cdx4, respectively. The lines carry Cdx transgenes under the transcriptional control of their own promoter/enhancer elements. Transgenic embryos show Cdx transcription at 8.5 to 8.7 days within normal spatial domains for Cdx...

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Identifiers

PMID: 18579683
DOI: 10.1242/dev.015909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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