Genome-wide association studies of cancer predisposition.

Abstract excerpt

Genome-wide association studies (GWAS) have now been performed in nearly all common malignancies and have identified more than 100 common genetic risk variants that confer a modest increased risk of cancer. For most discovered germline risk variants, the per allele effect size is small (<1.5) and the biologic mechanism of the detected association remains unexplained. Exceptions are the risk variants identified in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to JAK2 gene
• Share to KITLG gene
• Share to Genetic Predisposition to Disease