Article
Cancer genetics.
American journal of medical genetics - 22 Jul 2002
Knudson Alfred G
Abstract excerpt
Cancer is a genetic disease of somatic cells. Tumor karyotypes are rarely normal, and most show multiple abnormalities of both number and structure. The first direct evidence for this concept of cancer came from studies of tumor-specific translocations in leukemias and lymphomas, revealing the importance of oncogenes and the regulation of gene transcription in cancer. A second major source of information about...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.