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Article

Familial concordance of breast cancer pathology as an indicator of genotype in multiple-case families.

Genes, chromosomes & cancer - 1 Dec 2010

Balleine Rosemary L, Provan Pamela J, Pupo Gulietta M, Pathmanathan Nirmala, Cummings Margaret, Farshid Gelareh, Salisbury Elizabeth L, Bilous A Michael, Byth Karen, Mann Graham J

Abstract excerpt

The heterogeneity of multiple case breast cancer families that do not carry mutations in BRCA1 or BRCA2 (non-BRCA1/2 families) poses a challenge to the identification of breast cancer susceptibility genes. The aim of this study was to determine whether intrafamilial concordance in breast cancer pathology could identify subgroups of non-BRCA1/2 families with consistent genotypic features. Invasive breast cancers...

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Source

Identifiers

PMID: 20815029
DOI: 10.1002/gcc.20816

Genes

BRCA1
BRCA2
FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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