Article
Molecular and pathological characterization of inherited breast cancer.
Seminars in cancer biology - 1 Oct 2001
Borg A
Abstract excerpt
The two major breast cancer susceptibility genes, BRCA1 and BRCA2, account for the majority of familial breast-ovarian cancer, but only a modest proportion of breast cancer families without ovarian or male breast cancer. Search for additional breast cancer genes with traditional linkage analysis has so far been unsuccessful, probably due to genetic heterogeneity. Pooling of families of different ethnical,...
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