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Article

The Protein Network Surrounding the Human Telomere Repeat Binding Factors TRF1, TRF2, and POT1

25 Aug 2010

Abstract excerpt

Telomere integrity (including telomere length and capping) is critical in overall genomic stability. Telomere repeat binding factors and their associated proteins play vital roles in telomere length regulation and end protection. In this study, we explore the protein network surrounding telomere repeat binding factors, TRF1, TRF2, and POT1 using dual-tag affinity purification in combination with multidimensional...

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PMID: 20811636
DOI: 10.1371/journal.pone.0012407

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