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Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E

22 Oct 2014

Abstract excerpt

Burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) cells are erythroid progenitors traditionally defined by colony assays. We developed a flow cytometry-based strategy for isolating human BFU-E and CFU-E cells based on the changes in expression of cell surface markers during in vitro erythroid cell culture. BFU-E and CFU-E are characterized by...

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PMID: 25339359
DOI: 10.1182/blood-2014-07-588806

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