Article
Association of the intergenic single-nucleotide polymorphism rs10865331 (2p15) with ankylosing spondylitis in a Spanish population.
The Journal of rheumatology - 1 Nov 2010
Sánchez Alejandra, Szczypiorska Magdalena, Juanola Xavier, Bartolomé Nerea, Gratacós Jordi, Zarco Pedro, Collantes Eduardo, Artieda Marta, Martínez Antonio, Tejedor Diego, Mulero Juan
Abstract excerpt
OBJECTIVE: A recent genome-wide association study has identified 2 single-nucleotide polymorphisms (SNP) associated with ankylosing spondylitis (AS), rs10865331 (2p15) and rs2242944 (21q22). We assessed the association of these SNP with AS in a Spanish population. METHODS: Four hundred fifty-six patients with AS fulfilling the modified New York Criteria and 300 healthy donors were analyzed. Result. SNP rs10865331...
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