Article
Genetic effects of B3GNT2 on ankylosing spondylitis susceptibility and clinical manifestations in Taiwanese.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Jul 2022
Wang Chin-Man, Jan Wu Yeong-Jian, Lin Jing-Chi, Huang Li-Yu, Wu Jianming, Chen Ji-Yih
Abstract excerpt
BACKGROUND/PURPOSE: The intergenic SNP rs10865331 at 2p15 was identified as a major risk factor for ankylosing spondylitis (AS) susceptibility in genome-wide association studies (GWAS). B3GNT2 gene regulates polylactosamine synthesis is potentially functionally relevant to AS disease development. We investigated whether SNP rs10865331 and two B3GNT2 SNPs (rs11900673 and rs1136151) are associated with AS...
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