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Article

Determining the profiles and parameters for gene amplification testing of growth factor receptors in lung cancer.

International journal of cancer - 15 Aug 2013

Pros Eva, Lantuejoul Sylvie, Sanchez-Verde Lydia, Castillo Sandra D, Bonastre Ester, Suarez-Gauthier Ana, Conde Esther, Cigudosa Juan C, Lopez-Rios Fernando, Torres-Lanzas Juan, Castellví Josep, Ramon y Cajal Santiago, Brambilla Elisabeth, Sanchez-Cespedes Montse

Abstract excerpt

Growth factor receptors (GFRs) are amenable to therapeutic intervention in cancer and it is important to select patients appropriately. One of the mechanisms for activation of GFRs is gene amplification (GA) but discrepancies arising from the difficulties associated with data interpretation and t...

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Topics

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Share to Carcinoma, Non-Small-Cell Lung
Share to Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Immunohistochemistry

Share to In Situ Hybridization, Fluorescence

Share to Lung Neoplasms

Share to Real-Time Polymerase Chain Reaction

Share to Receptors, Growth Factor

Source

Identifiers

PMID: 23400671
DOI: 10.1002/ijc.28090

Genes

KIT
ERBB2
MET
FGFR1
PDGFRA
ALK
EGFR
FGFR2
FGFR3
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23400671-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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