Article
Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level.
Nature medicine - 1 Sept 2010
Bunnik Evelien M, Euler Zelda, Welkers Matthijs R A, Boeser-Nunnink Brigitte D M, Grijsen Marlous L, Prins Jan M, Schuitemaker Hanneke
Abstract excerpt
By comparing HIV-1 variants from people who became infected at the beginning of the epidemic and from people who have recently contracted the virus, we observed an enhanced resistance of the virus to antibody neutralization over time, accompanied by an increase in the length of the variable loops...
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