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Article

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

18 Mar 2003

Abstract excerpt

A recombinant virus assay was used to characterize in detail neutralizing antibody responses directed at circulating autologous HIV in plasma. Examining serial plasma specimens in a matrix format, most patients with primary HIV infection rapidly generated significant neutralizing antibody responses to early (0-39 months) autologous viruses, whereas responses to laboratory and heterologous primary strains were...

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Identifiers

PMID: 12644702
DOI: 10.1073/pnas.0630530100

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