Article
Genetic variations in TERT-CLPTM1L genes and risk of squamous cell carcinoma of the head and neck.
Carcinogenesis - 1 Nov 2010
Liu Zhensheng, Li Guojun, Wei Sheng, Niu Jiangong, Wang Li-E, Sturgis Erich M, Wei Qingyi
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) of TERT-rs2736098 (C > T) and CLPTM1L-rs401681(C > T) at the 5p15.33 locus are significantly associated with cancer risk as reported in genome-wide association studies (GWAS), but there are no reported studies for squamous cell carcinoma of the head and neck (SCCHN). In a case-control study of 1079 SCCHN cases and 1115 cancer-free controls of non-Hispanic whites who were...
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