Article
Common genetic variants in TERT contribute to risk of cervical cancer in a Chinese population.
Molecular carcinogenesis - 1 Oct 2012
Wang Sumin, Wu Jiangping, Hu Lingmin, Ding Chenyue, Kan Yanjing, Shen Yan, Chen Xiaojun, Shen Hongbing, Guo Xirong, Hu Zhibin
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) of TERT rs2736098, rs2736100, and CLPTM1L rs402710 at 5p15.33 are significantly associated with risk of a spectrum of cancers. However, cervical cancer has been rarely evaluated. In this study, we genotyped the three SNPs in a case-control study with 1,033 cervical cancer cases and 1,053 cancer-free controls in a Chinese population. Logistic regression analyses showed that...
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