Tailored Physiotherapy Management of Motor Neuron Disease with Predominant Lower Motor Neuron Involvement in a Young Adult: A Case Report

Abstract excerpt

<title>Abstract</title> <p>Background: Motor neuron disease (MND) is a progressive neurodegenerative disorder involving degeneration of upper and/or lower motor neurons, resulting in muscle weakness and functional decline. Progressive muscular atrophy (PMA) represents a lower motor neuron–predominant phenotype within the MND spectrum and commonly presents with distal limb weakness and progressive disability. <h4...

Topics

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• Cyclic AMP Response Element-Binding Protein
• Guanine Nucleotide Exchange Factors
• Motor Neuron Disease
• Muscular Atrophy, Spinal
• Receptors, Androgen
• SMN Complex Proteins
• Superoxide Dismutase-1
• Trinucleotide Repeat Expansion

Identifiers and source

Literature Corpus work

66ab2ee6-fc68-5724-968c-849fc910ad6d

DOI

10.21203/rs.3.rs-8945808/v1