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Article

Physical trapping of HIV-1 synaptic complex by different structural classes of integrase strand transfer inhibitors.

Biochemistry - 28 Sept 2010

Pandey Krishan K, Bera Sibes, Vora Ajaykumar C, Grandgenett Duane P

Abstract excerpt

Raltegravir is an FDA approved inhibitor directed against human immunodeficiency virus type 1 (HIV-1) integrase (IN). In this study, we investigated the mechanisms associated with multiple strand transfer inhibitors capable of inhibiting concerted integration by HIV-1 IN. The results show raltegr...

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Identifiers

PMID: 20799722
DOI: 10.1021/bi100514s
PMCID: PMC2965028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20799722-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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