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Article

Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous.

Genetics - 1 Dec 1990

Voelkel-Meiman K, Roeder G S

Abstract excerpt

The recombination-stimulating sequence, HOT1, corresponds to the promoter of transcription by yeast RNA polymerase I. The effect of HOT1 on mitotic interchromosomal recombination was examined in diploid strains carrying a heterozygous URA3 gene on chromosome III. The frequency of Ura- recombinants was increased 20-fold when HOT1 was inserted into the chromosome III copy marked with URA3, at a location 48 kbp...

Topics

Chromosome Mapping
Chromosomes, Fungal
DNA Repair
Diploidy
Gene Conversion
Genes, Fungal
Genotype
Homozygote
Promoter Regions, Genetic
RNA Polymerase I
Regulatory Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Transcription, Genetic

Source

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Identifiers

PMID: 2076817
DOI: 10.1093/genetics/126.4.851
PMCID: PMC1204283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2076817-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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