Article
Gene conversion tracts stimulated by HOT1-promoted transcription are long and continuous.
Genetics - 1 Dec 1990
Voelkel-Meiman K, Roeder G S
Abstract excerpt
The recombination-stimulating sequence, HOT1, corresponds to the promoter of transcription by yeast RNA polymerase I. The effect of HOT1 on mitotic interchromosomal recombination was examined in diploid strains carrying a heterozygous URA3 gene on chromosome III. The frequency of Ura- recombinants was increased 20-fold when HOT1 was inserted into the chromosome III copy marked with URA3, at a location 48 kbp...
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