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Reproductive aging in invertebrate genetic models

1 Aug 2010

Abstract excerpt

The invertebrate genetic systems of Caenorhabditis elegans and Drosophila melanogaster are emerging models to understand the underlying mechanisms of reproductive aging and the relationship between reproduction and lifespan. Both animals show progressive decline in egg production beginning at early middle age, caused in part by reduction in germline stem cell proliferation as well as in survival of developing...

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PMID: 20738285
DOI: 10.1111/j.1749-6632.2010.05522.x

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