Article
TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.
PLoS genetics - 1 Dec 2009
Luo Shijing, Shaw Wendy M, Ashraf Jasmine, Murphy Coleen T
Abstract excerpt
Female reproductive cessation is one of the earliest age-related declines humans experience, occurring in mid-adulthood. Similarly, Caenorhabditis elegans' reproductive span is short relative to its total life span, with reproduction ceasing about a third into its 15-20 day adulthood. All of the...
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