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Article

P-glycoprotein in the placenta: expression, localization, regulation and function.

Reproductive toxicology (Elmsford, N.Y.) - 1 Oct 2006

Ceckova-Novotna Martina, Pavek Petr, Staud Frantisek

Abstract excerpt

Detailed understanding of the mechanisms employed in transfer of drugs across the placenta is essential for optimization of pharmacotherapy during pregnancy. Disclosure of drug efflux transporters as an "active component" of the placental barrier has brought new important insights into the field of transplacental pharmacokinetics. P-glycoprotein (P-gp, MDR1) is the first discovered and so far the best...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Maternal-Fetal Exchange

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 16563694
DOI: 10.1016/j.reprotox.2006.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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