Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal‐Fetal Drug Transfer

Abstract excerpt

Tremendous efforts have been directed to investigate the ontogeny of drug transporters in fetuses, neonates, infants, and children based on their importance for understanding drug pharmacokinetics. During development (ie, in the fetus and newborn infant), there is special interest in transporters expressed in the placenta that modulate placental drug transfer. Many of these transporters can decrease or increase...

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