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Article

ATP-binding cassette transporters in reproduction: a new frontier

5 Nov 2015

Abstract excerpt

BACKGROUND: The transmembrane ATP-binding cassette (ABC) transporters actively efflux an array of clinically relevant compounds across biological barriers, and modulate biodistribution of many physiological and pharmacological factors. To date, over 48 ABC transporters have been identified and shown to be directly and indirectly involved in peri-implantation events and fetal/placental development. They efflux...

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PMID: 26545808
DOI: 10.1093/humupd/dmv049

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