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Developmental expression of drug metabolizing enzymes and transporter proteins in human placenta and fetal tissues

28 Sept 2009

Abstract excerpt

Transporter proteins and xenobiotic metabolizing enzymes have a crucial role in the fate of xenobiotics in human body. The expression in human placenta and fetal tissues of the proteins most commonly participating in pharmaco/toxicokinetics is reviewed. In case human data are not available, relevant animal data are included. Among transporter proteins ABC transporters, monoamine transporters and organic anion...

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Drug Transport and Resistance Mechanisms
Pharmacological Effects and Toxicity Studies
Pregnancy and Medication Impact

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19785513
DOI: 10.1517/17425250903304049

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