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Article

Transformation of <i>Candida albicans</i> with a synthetic hygromycin B resistance gene

24 Aug 2010

Abstract excerpt

Synthetic genes that confer resistance to the antibiotic nourseothricin in the pathogenic fungus Candida albicans are available, but genes conferring resistance to other antibiotics are not. We found that multiple C. albicans strains were inhibited by hygromycin B, so we designed a 1026 bp gene (CaHygB) that encodes Escherichia coli hygromycin B phosphotransferase with C. albicans codons. CaHygB conferred...

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PMID: 20737428
DOI: 10.1002/yea.1813

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