Characterization of the<i>CaNAG3</i>,<i>CaNAG4</i>, and<i>CaNAG6</i>genes of the pathogenic fungus<i>Candida albicans</i>: possible involvement of these genes in the susceptibilities of cytotoxic agents

Abstract excerpt

CaNAG3, CaNAG4, and CaNAG6 form a gene cluster with CaNAG1 CaNAG2 and CaNAG5 that are responsible for glucosamine-6-phosphate deaminase, N-acetylglucosamine-phosphate deacetylase and N-acetylglucosamine kinase, but their functions largely remain unclear. In this study, Candida albicans cells carrying null mutations in either CaNAG3, CaNAG4, or CaNAG6 were generated and characterized. They showed increased...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antifungal resistance and susceptibility
• Share to Fungal Infections and Studies
• Share to Pneumocystis jirovecii pneumonia detection and treatment