Article
High-resolution analysis of chromosomal imbalances using the Affymetrix 10K SNP genotyping chip.
Genomics - 1 Mar 2005
Herr Alexander, Grützmann Robert, Matthaei Anja, Artelt Juliane, Schröck Evelin, Rump Andreas, Pilarsky Christian
Abstract excerpt
Array-based comparative genome hybridization is a powerful tool for detecting chromosomal imbalances at high resolution. However, the design and setup of such arrays are time consuming and expensive and thus worthwhile only when large numbers of arrays will be processed. To provide a feasible solution, we have developed an algorithm that renders the publicly available Affymetrix 10K SNP genotyping chip useful for...
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