Detection of chromosomal aberrations in renal tumors: a comparative study of conventional cytogenetics and virtual karyotyping with single-nucleotide polymorphism microarrays.

Abstract excerpt

CONTEXT: -Renal epithelial neoplasms have characteristic chromosomal imbalances, and we have shown previously that virtual karyotypes derived from single-nucleotide polymorphism microarrays can be performed on formalin-fixed, paraffin-embedded tissue. OBJECTIVE: -To perform a direct comparison of virtual and conventional karyotypes to evaluate concordance of results. DESIGN: -Twenty archival formalin-fixed,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carcinoma, Papillary
• Share to Carcinoma, Renal Cell