Article
Doubles game: Src-Stat3 versus p53-PTEN in cellular migration and invasion.
Molecular and cellular biology - 1 Nov 2010
Mukhopadhyay Utpal K, Mooney Patrick, Jia Lilly, Eves Robert, Raptis Leda, Mak Alan S
Abstract excerpt
We have recently shown that Src induces the formation of podosomes and cell invasion by suppressing endogenous p53, while enhanced p53 strongly represses the Src-induced invasive phenotype. However, the mechanism by which Src and p53 play antagonistic roles in cell invasion is unknown. Here we sh...
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