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Article

ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells.

The Journal of biological chemistry - 29 Oct 2010

Drake Justin M, Barnes J Matthew, Madsen Joshua M, Domann Frederick E, Stipp Christopher S, Henry Michael D

Abstract excerpt

Metastasis involves the invasion of cancer cells across both the extracellular matrix and cellular barriers, and an evolving theme is that epithelial-to-mesenchymal transition (EMT) may mediate invasive cellular behavior. Previously, we isolated and analyzed a subpopulation of PC-3 prostate cance...

Read the complete abstract on PubMed

Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Integrin beta4

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Source

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Identifiers

PMID: 20729552
DOI: 10.1074/jbc.M110.136044
PMCID: PMC2962494

Genes

ZEB1
ITGB4
LAMC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20729552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells.PMID 20729552Read ↗

ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells.Semantic proximity Read ↗

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