Article

TEAD1 regulates ITGA1 and ITGA2 to control prostate cancer progression

2023-04-12

Abstract excerpt

<h4>ABSTRACT</h4> The extracellular matrix (ECM) undergoes significant changes during prostate cancer (PCa) progression and actively regulates PCa growth and invasion. Here, we performed a meta-analysis of PCa cohorts and found that downregulation or loss of ITGA1 and ITGA2 integrin genes was associated with tumor progression to metastasis and poor prognosis in PCa patients. Genomic deletion of both α1- and α2-...

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Literature Corpus work: 69a5424a-1d4b-5d84-b983-5035d4d05ae9
DOI: 10.1101/2023.04.12.536554

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