Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers

10 Mar 2021

Abstract excerpt

BACKGROUND: Genomic analysis is essential for risk stratification in patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Whole-genome sequencing is a potential replacement for conventional cytogenetic and sequencing approaches, but its accuracy, feasibility, and clinical utility have not been demonstrated. METHODS: We used a streamlined whole-genome sequencing approach to obtain genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Chronic Myeloid Leukemia Treatments
Share to Genomics and Rare Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33704937
DOI: 10.1056/nejmoa2024534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid CancersPMID 33704937Read ↗

Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.Semantic proximity Read ↗

Genomics of AML: clinical applications of next-generation sequencing.Semantic proximity Read ↗

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.Semantic proximity Read ↗

AML genomics for the clinician.Semantic proximity Read ↗

Evaluation of Long-Read Genome Sequencing for Genomic Profiling of Myeloid Cancers.Semantic proximity Read ↗

Analytical Evaluation of Whole Genome Sequencing for Acute Myeloid LeukemiaSemantic proximity Read ↗

Advances in DNA/RNA Sequencing and Their Applications in Acute Myeloid Leukemia (AML)Semantic proximity Read ↗

Next Generation Sequencing of Acute Myeloid Leukemia: Influencing PrognosisSemantic proximity Read ↗

Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.Semantic proximity Read ↗

Analytical validation and performance characteristics of a 48-gene next-generation sequencing panel for detecting potentially actionable genomic alterations in myeloid neoplasmsSemantic proximity Read ↗

Molecular genetics of AML.Semantic proximity Read ↗

Next-Generation Sequencing of Cancer Genomes: Back to the FutureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.