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Article

Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Feb 2011

Marcucci Guido, Haferlach Torsten, Döhner Hartmut

Abstract excerpt

Molecular analyses of leukemic blasts from patients with acute myeloid leukemia (AML) have revealed a striking heterogeneity with regard to the presence of acquired gene mutations and changes in gene and microRNA expression. Multiple submicroscopic genetic alterations with prognostic significance have been discovered. Application of gene- and microRNA profiling has identified genome-wide expression signatures...

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Source

Identifiers

PMID: 21220609
DOI: 10.1200/JCO.2010.30.2554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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