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Article

In vivo assembly of yeast mitochondrial alpha-ketoglutarate dehydrogenase complex.

Molecular and cellular biology - 1 Aug 1991

Repetto B, Tzagoloff A

Abstract excerpt

The assembly of alpha-ketoglutarate dehydrogenase complex (KGDC) has been studied in wild-type Saccharomyces cerevisiae and in respiratory-deficient strains (pet) with mutations in KGD1 and KGD2, the structural genes for alpha-ketoglutarate dehydrogenase (KE1) and dihydrolipoyl transsuccinylase (KE2) components, respectively. Mutants unable to express KE1 or KE2 form partial complexes similar to those reported in...

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Identifiers

PMID: 2072900
DOI: 10.1128/mcb.11.8.3931-3939.1991
PMCID: PMC361187

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