Structure and regulation of KGD2, the structural gene for yeast dihydrolipoyl transsuccinylase.

doi:10.1128/mcb.10.8.4221-4232.1990

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Article

Structure and regulation of KGD2, the structural gene for yeast dihydrolipoyl transsuccinylase.

Molecular and cellular biology - 1 Aug 1990

Repetto B, Tzagoloff A

Abstract excerpt

Yeast mutants assigned to the pet complementation group G104 were found to lack alpha-ketoglutarate dehydrogenase activity as a result of mutations in the dihydrolipoyl transsuccinylase (KE2) component of the complex. The nuclear gene KGD2, coding for yeast KE2, was cloned by transformation of E2...

Topics

Acyltransferases
Amino Acid Sequence
Base Sequence
Cloning, Molecular
Gene Expression Regulation, Fungal
Genes, Fungal
Genomic Library
Genotype
Molecular Sequence Data
Mutation
Phenotype
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Recombinant Fusion Proteins

Restriction Mapping

Saccharomyces cerevisiae

Sequence Homology, Nucleic Acid

Transcription, Genetic

Source

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Identifiers

PMID: 2115121
DOI: 10.1128/mcb.10.8.4221-4232.1990
PMCID: PMC360958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2115121-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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