Article
Mapping of functional interactions between domains of the animal fatty acid synthase by mutant complementation in vitro.
Biochemistry - 25 Feb 1997
Joshi A K, Witkowski A, Smith S
Abstract excerpt
Polypeptides of the animal fatty acid synthase (FAS) consist of three amino-terminal catalytic domains, beta-ketoacyl synthase, malonyl/acetyltransacylase, and dehydrase, separated by a 600-residue structural core from four carboxyl-terminal catalytic domains, enoyl reductase, beta-ketoacyl reduc...
Topics
- Animals
- Fatty Acid Synthases
- Models, Molecular
- Mutation
- Peptide Mapping