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Article

Double stranded RNA-dependent protein kinase is involved in osteoclast differentiation of RAW264.7 cells in vitro.

Experimental cell research - 15 Nov 2010

Teramachi Junpei, Morimoto Hiroyuki, Baba Ryoko, Doi Yoshiaki, Hirashima Kanji, Haneji Tatsuji

Abstract excerpt

Double-stranded RNA-dependent protein kinase (PKR) plays a critical role in antiviral defence of the host cells. PKR is also involved in cell cycle progression, cell proliferation, cell differentiation, tumorigenesis, and apoptosis. We previously reported that PKR is required for differentiation and calcification of osteoblasts. However, it is unknown about the role of PKR in osteoclast differentiation. A...

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Identifiers

PMID: 20728438
DOI: 10.1016/j.yexcr.2010.08.006

Genes

STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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