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Article

The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264.7 cells.

The Journal of biological chemistry - 2 Apr 2004

Hirotani Hiroaki, Tuohy Nathaniel A, Woo Je-Tae, Stern Paula H, Clipstone Neil A

Abstract excerpt

Although best known for its role in T lymphocyte activation, the calcineurin/nuclear factor of activated T cells (NFAT) signaling pathway is also known to be involved in a wide range of other biological responses in a variety of different cell types. Here we have investigated the role of the calcineurin/NFAT signaling pathway in the regulation of osteoclast differentiation. Osteoclasts are bone-resorbing...

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Identifiers

PMID: 14722106
DOI: 10.1074/jbc.M213067200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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