Article
Effects of tannic acid on spontaneous and induced somatic mutations in Drosophila melanogaster.
Mutagenesis - 1 May 1991
Szakmary A, Knasmüller S
Abstract excerpt
The effects of tannic acid (TA) alone and in combination with direct acting chemical genotoxins and gamma-radiation were investigated in Somatic Mutation and Recombination Tests (SMARTs) using Drosophila melanogaster. Treatment with TA alone (2.5-15 mmol/l) resulted in a moderate but dose dependent induction of mosaic spots in males and females, indicating that the compound possesses mutagenic and recombinogenic...
Topics
- Animals
- Drosophila melanogaster
- Drug Synergism
- Eye Color
- Female
- Gamma Rays
- Hydrolyzable Tannins
- Male
- Mitosis
- Mosaicism
- Mutagenesis
- Mutagenicity Tests
