Article
Two new RHD alleles with deletions spanning multiple exons.
Transfusion - 1 Mar 2021
Matteocci Antonella, Monge-Ruiz Jorge, Stef Marianne, Apraiz Izaskun, Herrera-Del-Val Lara, Mancuso Tommaso, Fennell Katie, Lopez Monica, Larizgoitia-Martin Yolanda, Nespoli Guido, Rubia-Tejero Montserrat, Collaretti Angela, Pierelli Luca, Ochoa-Garay Gorka
Abstract excerpt
BACKGROUND: The most common large-deletion RHD allele (RHD*01N.01) includes the entire coding sequence, intervening regions and untranslated regions. The rest of large-deletion RHD alleles reported to-date consist of single-exon deletions, such as RHD*01N.67 which includes exon 1. MATERIALS AND METHODS: Samples from two donors with RhD-negative serology yielded unclear or inconclusive results when subject to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.