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Article

Computational identification of cancer susceptibility loci.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Laakso Marko, Karinen Sirkku, Lehtonen Rainer, Hautaniemi Sampsa

Abstract excerpt

The identification of novel cancer susceptibility syndromes and genes from very limited numbers of study individuals has become feasible through the use of high-throughput genotype microarrays. With such an approach, highly sensitive genome-wide computational methods are needed to identify the regions of interest. We have developed novel methods to identify and compare homozygous and compound heterozygous regions...

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PMID: 20721739
DOI: 10.1007/978-1-60761-759-4_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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