Article
Candidate single nucleotide polymorphism selection using publicly available tools: a guide for epidemiologists.
American journal of epidemiology - 15 Oct 2006
Bhatti Parveen, Church Deanna M, Rutter Joni L, Struewing Jeffery P, Sigurdson Alice J
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most common form of human genetic variation, with millions present in the human genome. Because only 1% might be expected to confer more than modest individual effects in association studies, the selection of predictive candidate variants for complex disease analyses is formidable. Technologic advances in SNP discovery and the ever-changing annotation of the genome...
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