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ELISA genotyping of hepatitis B virus in China with antibodies specific for genotypes B and C.

Scientific reports - 12 Oct 2024

Li Yumin, Wang Li, Cheng Huanyi, Chi Xiumei, Huang Qingrui, Lv Pinxin, Zhang Wenyi, Niu Junqi, Wen Xiaoyu, Liu Zhenning

Abstract excerpt

Hepatitis B virus (HBV) causes hepatitis B (HB) and distinct HBV genotypes can lead to different prognoses. However, HBV genotyping is rarely done in clinics, because the traditional method by PCR-based DNA sequencing is impractical for clinical diagnosis with tedious process and low success rate. Herein, we have established an ELISA-based genotyping method to quickly determine the HBV genotypes of HB patients in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39396069
DOI: 10.1038/s41598-024-76023-7
PMCID: PMC11470951

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