Article
Simultaneous quantification and genotyping of hepatitis B virus for genotypes A to G by real-time PCR and two-step melting curve analysis.
Journal of clinical microbiology - 1 Dec 2006
Liu Wen-Chun, Mizokami Masashi, Buti Maria, Lindh Magnus, Young Kung-Chia, Sun Koun-Tem, Chi Yun-Chan, Li Hsi-Hsien, Chang Ting-Tsung
Abstract excerpt
Both the viral titer and the genotype significantly determine clinical outcomes and responses to antiviral treatment in chronic hepatitis B virus (HBV) infection. A method was developed for large-scale A-to-G genotyping with simultaneous viral quantification. The assay was run on a LightCycler in...
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