Yeast protein-protein interaction binding sites: prediction from the motif-motif, motif-domain and domain-domain levels.

Abstract excerpt

Interacting proteins can contact with each other at three different levels: by a domain binding to another domain, by a domain binding to a short protein motif, or by a motif binding to another motif. In our previous work, we proposed an approach to predict motif-motif binding sites for the yeast interactome by contrasting high-quality positive interactions and high-quality non-interactions using a simple...

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