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Article

Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.

World journal of gastroenterology - 21 Aug 2010

Mwinyi Jessica, Wenger Christa, Eloranta Jyrki J, Kullak-Ublick Gerd A

Abstract excerpt

AIM: To study whether the glucocorticoid receptor (GR/NR3C1) gene haplotypes influence the steroid therapy outcome in inflammatory bowel disease (IBD). METHODS: We sequenced all coding exons and flanking intronic sequences of the NR3C1 gene in 181 IBD patients, determined the single nucleotide polymorphisms, and predicted the NR3C1 haplotypes. Furthermore, we investigated whether certain NR3C1 haplotypes are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20712049
DOI: 10.3748/wjg.v16.i31.3888
PMCID: PMC2923762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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