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Article

Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases.

Journal of clinical gastroenterology - 1 Jan 2011

De Iudicibus Sara, Stocco Gabriele, Martelossi Stefano, Londero Margherita, Ebner Egle, Pontillo Alessandra, Lionetti Paolo, Barabino Arrigo, Bartoli Fiora, Ventura Alessandro, Decorti Giuliana

Abstract excerpt

BACKGROUND: Glucocorticoids (GCs) are used in moderate-to-severe inflammatory bowel diseases (IBD) but their effect is often unpredictable. AIM: To determine the influence of 4 polymorphisms in the GC receptor [nuclear receptor subfamily 3, group C, member 1 (NR3C1)], interleukin-1β (IL-1β), and NACHT leucine-rich-repeat protein 1 (NALP1) genes, on the clinical response to steroids in pediatric patients with IBD....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20697295
DOI: 10.1097/MCG.0b013e3181e8ae93

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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